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Remarkably, in both animal models and cell investigations, RF deprivation has been linked to the prevention of tumor growth (94) ( Table 2 )

Chen W-A, Chang D-Y, Chen B-M, Lin Y-C, Barenholz Y, Roffler SR

In contrast, ARG2 is expressed in mitochondria of multiple tissues, with the most abundant expression in the kidney and prostate, and mediates arginine/ornithine balance